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賴氨酸丙酰化抗體偶聯樹脂
杭州景杰生物科技有限公司
Anti-propionyllysine antibody conjugated agarose beads

Cat#:

PTM-202

Ab Type:

P

Applications:

IAC IP

Species:

All

Price: (0.5 ml)

22432.00

Price: (0.1 ml)

?7800.00


Product Description

The rabbit-derived polyclonal anti-propionyllysine antibodies are crosslinked to agarose with stable amide linkages. In the global proteomic screening of lysine propionylation, the product was well utilized as affinity matrix to specifically capture the peptides/proteins bearing propionyllysine residues in all species.


Source/Purification

/

Specificity

All

Recommended Applications

Protein/peptide immunoprecipitation for lysine propionylation proteomics; Immuno-affinity chromatography.


??

Recommended antibody dilution

/

Important

/

Scientific Description

Propionylation of lysine, structurally similar to lysine acetylation, is an newly identified reversible modification controlling protein activity. The reversible lysine propionylation has been well demonstrated in both prokaryotes and eukaryotes in wide ranges of proteins including histones and non-histone substrates, such as p53. It is speculated that lysine propionylation plays a vital role in the regulation of multiple cellular processes including chromatin dynamics and plasticity and DNA transcriptional regulation by sharing the same regulatory enzymes with lysine acetylation or with unique regulatory enzymes.


Storage & Stability

Store product at -20oC. Avoid repeated freeze/thaw. Antibody is supplied in PBS with 50% glycerol and 0.01% sodium azide.Stable for 12 months from date of receipt.


**Research purposes only. Not intended to be used for therapeutic or diagnostic purposes in humans or animals.


Sun M,et al.Characterization of Protein Lysine Propionylation in Escherichia coli: Global Profiling, Dynamic Change, and Enzymatic Regulation.?J Proteome Res.?2016 Dec 2;15(12):4696-4708. Epub 2016 Nov 10.

Protein/peptide immunoprecipitation for lysine propionylation proteomics; Immuno-affinity chromatography.

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